While medication can be an effective means of treating depression, it can also lead to tolerance, withdrawal and subsequent dependency. Additionally, some recent data has shown that who used antidepressants had a 14 percent higher risk of heart attacks and strokes and a 33 percent greater risk of death. These drugs, after prolonged use, can create long-term changes in the brain’s chemistry that create a whole different set of problems. TMS therapy also may be preferable to antidepressants because you don’t have to engage with the therapy every day, unlike with pharmacological interventions. When administered alongside therapy, counseling and occupational therapies, TMS can be a game-changing advantage for depression sufferers who have been impacted by substance use disorder.